THEMES

High albumin in the urine

High albumin in the urine

Your tests found a condition of high albumin in the urine, and you don't know what that can mean?
Well, it being understood that any clarification can only be shared with your referring doctor, we can first of all remind you how thealbumin be one plasma protein which is found in abundance in human blood, facilitating some functions such as transporting thyroid and steroid hormones, or maintaining the right oncotic pressure.

Therefore, if albumin is found in high quantities in urinalysis, it is possible that something is not working properly in the kidneys. But what? And above all, what to do in case of high albumin? Certainly it will be necessary to consult your doctor.

It intervenes in the transport of numerous endogenous substances such as direct bilirubin or conjugated bilirubin.

Albumin values ​​in the urine

In order to understand when it can be high albumin in the urine, it is good to remember that this protein in the urine should not be present, and that therefore the report of the laboratory analyzes should give the albumin level as "absent" or minimal.

In summary, it is still possible to determine as the physiological value that of an albumin in the urine between 2 and 15 milligrams in 24 hours, while we can speak of microalbuminuria if the values ​​are between 15 and 300 milligrams in 24 hours. We will talk about macroalbuminuria, or chronic albuminuria, if instead the values ​​are higher than 300 milligrams in 24 hours.

Evidently, although both the conditions of microalbuminuria and those of macroalbuminuria are attributable tohigh albumin in the urine, is the second scenario that should set off a few more alarm bells.

Causes high albumin in the urine

But what are the causes of high albumin in the urine?
In reality, the range of determinants is quite heterogeneous. For example, a slight increase in values ​​can be considered physiological and reversible, i.e. considered by transitory situations and not originating from diseases: pregnancy, physical exertion, colds, flu, menstrual cycle and standing are just some of the causes of a tendential and physiological increase albumin.

Evidently, if the increase is more significant and not transitory, we are faced with a condition of albuminuria which is linked to clinical conditions, generally affecting the kidneys.

In this context, the list of causes is very extensive. Didactically, we can exemplify by identifying a first group of causes in intoxications, venous congestions, heart failure and, again, dehydration, poor protein diet or perhaps in hypertensive states and anemia: these are conditions defined as "pre- renal ", to distinguish them from a second group, called instead of" renal "origin.

In this context we can well trace all the causes that are inherent in pathological kidney problems, such as carcinoma, destructive kidney lesions, cases of poisoning, TB and glomerulonephritis. It is however possible, on the sidelines, that there may also be other conditions such as kidney pelvis infection, cystitis, urethritis or prostatitis.

In case of uric acid (high uric acid) there can be accumulations in the kidneys causing kidney stones and or kidney failure resulting in high albumin. As is clear, the clinical context is very varied and the advice of a doctor is essential.

Test for albumin in the urine

As can be guessed, if the doctor suspects that there is high albumin in the urine, will prescribe a laboratory test on them, carried out with a simple urinary sample, to be submitted to the analysis laboratory.

However, the methods of analysis can be different. Depending on the results you want to aim for, the doctor could, for example, propose the collection of urine at any time of the day, and at the same time point to the dosage of creatinine, one of the substances that are filtered and expelled by the kidneys in physiological conditions.

It is also possible that the doctor may suggest the collection of the first urine in the morning, as generally happens, or the collection of urine throughout the day (i.e. the one produced within 24 hours) to be carried out in special containers that are easily available in Pharmacy.

That said, special conditions for urine collection are not normally required to know whether or not there is high albumin. However, it is advisable not to collect urine after particularly intense physical exertion (such as those caused by sports), to ensure that the results are not misleading and distorted by this element.
Once the results have been obtained, it will be advisable to share them with your doctor, who can use them to be able to carry out an initial confirmation of albuminuria, and possibly request further tests in order to arrive at a more complete diagnosis on the scenario of interest.

For other causes and information, the update on albumin analysis is available: high albumin.


Video: CKD Management: Identify and Monitor - Urine Albumin (May 2021).